Data set containing historical information for placebo for a phase
II trial of ankylosing spondylitis patients. The primary efficacy
endpoint was the percentage of patients with a 20% response
according to the Assessment of SpondyloArthritis international
Society criteria for improvement (ASAS20) at week 6.
A data frame with 8 rows and 3 variables:
- study
study
- n
study size
- r
number of events
References
Baeten D, others (2013).
“Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial.”
The Lancet, 382(9906), 1705–1713.
Examples
.user_mc_options <- options()
set.seed(34563)
map_AS <- gMAP(cbind(r, n - r) ~ 1 | study,
family = binomial,
data = AS,
tau.dist = "HalfNormal", tau.prior = 1,
beta.prior = 2
)
#> Assuming default prior location for beta: 0
## Recover user set sampling defaults
options(.user_mc_options)