Bayesian logistic regression model with optional EXchangeability-NonEXchangeability parameter modelling for flexible borrowing from historical or concurrent data-sources. The safety model can guide dose-escalation decisions for adaptive Oncology phase I dose-escalation trials which involve an arbitrary number of drugs.
Getting Started
To get a quick overview over the package functionality, please refer to the introductory vignette. An additional vignette discusses the use of historical data via the meta-analytic-approach.