Model generated PK data to mimic an orally administered small molecule. Simulated single dose administration ranging from 100 mg to 1600 mg.
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A data frame with the following 16 columns:
column 1: | ID | numeric; unique subject ID |
column 2: | TIME | numeric; time relative to first drug administration |
column 3: | NOMTIME | numeric; nominal time |
column 4: | TIMEUNIT | character; unit of TIME |
column 5: | AMT | numeric; dosing amount (for dosing events) in mg |
column 6: | LIDV | numeric; observation on a linear scale (observation type determined by CMT), units determined by EVENTU column |
column 7: | MDV | numeric; missing dependent variable |
(1 if missing, 0 otherwise) | column 8: | CMT |
integer; compartment number (determines observation type): | ||
CMT 1 = Dosing event | ||
CMT 2 = PK concentration | column 9: | NAME |
character; description of event | column 10: | EVENTU |
character; unit for observation | column 11: | CENS |
integer; censored values (0 = not censored, 1 = censored) | column 12: | EVID |
integer; event ID (0 = observation, 1 = dosing event) | column 13: | WEIGHTB |
numeric; baseline body weight (kg) | column 14: | SEX |
character; sex | column 15: | TRTACT |
factor; treatment group label | column 16: | DOSE |