Model generated PK data to mimic an orally administered small molecule. Simulated single dose administration ranging from 100 mg to 1600 mg.



A data frame with the following 16 columns:

column 1:IDnumeric; unique subject ID
column 2:TIMEnumeric; time relative to first drug administration
column 3:NOMTIMEnumeric; nominal time
column 4:TIMEUNITcharacter; unit of TIME
column 5:AMTnumeric; dosing amount (for dosing events) in mg
column 6:LIDVnumeric; observation on a linear scale (observation type determined by CMT), units determined by EVENTU column
column 7:MDVnumeric; missing dependent variable
(1 if missing, 0 otherwise)column 8:CMT
integer; compartment number (determines observation type):
CMT 1 = Dosing event
CMT 2 = PK concentrationcolumn 9:NAME
character; description of eventcolumn 10:EVENTU
character; unit for observationcolumn 11:CENS
integer; censored values (0 = not censored, 1 = censored)column 12:EVID
integer; event ID (0 = observation, 1 = dosing event)column 13:WEIGHTB
numeric; baseline body weight (kg)column 14:SEX
character; sexcolumn 15:TRTACT
factor; treatment group labelcolumn 16:DOSE