Simulated scRNA-seq trajectory with condition-dependent differential abundance

A simulated toy scRNA-seq dataset with a linear trajectory across 10 milestones, two conditions (A and B) with varying proportions per milestone, and three replicates per condition. Generated with dyntoy::generate_dataset() using set.seed(42).

Usage

data(sim_trajectory_tdr)

Format

A list with three elements:

sce

A SingleCellExperiment object (500 genes x 5000 cells) with assays counts and logcounts, colData containing cell metadata (cell_id, group_id, Condition, Replicate, Sample), and a PCA reduced dimension (50 components).

meta

A data.frame of per-cell metadata with columns cell_id, group_id, Condition, Replicate, and Sample.

pt

A numeric vector of pseudotime values (princurve arc-length) for each cell.

Source

Generated by data-raw/sim_trajectory_tdr.R, which reproduces the simulation from inst/analysis/sim_scRNAseq_trajectory_tdr.R.